Arsenal have been handed a tough assignment in the quarter-finals of the Europa League after being drawn against Napoli, while Chelsea will face Slavia Prague.
In the other two ties, there is an all-Spanish tie featuring Villareal taking on Valencia, while three-time runners-up Benfica will take on Eintracht Frankfurt.
The first legs of the ties will take place on April 11, with the return legs seven days later on April 18.
Europa League Quarter-final Draw
Napoli v Arsenal
Villareal v Valencia
Benfica v Eintracht Frankfurt
Slavia Prague v Chelsea